{"id":1797,"date":"2022-10-06T16:52:25","date_gmt":"2022-10-06T07:52:25","guid":{"rendered":"https:\/\/peptistar.com\/?page_id=1797"},"modified":"2022-10-20T13:59:05","modified_gmt":"2022-10-20T04:59:05","slug":"microwave","status":"publish","type":"page","link":"https:\/\/peptistar.com\/en\/technology\/microwave\/","title":{"rendered":"MW SPPS Method"},"content":{"rendered":"<div class=\"page-pretitle-blue\">\n<p>Peptide API Manufacturing Technologies<\/p>\n<\/div>\n<h2 class=\"page-title page-title-bottom-short\">MW SPPS Method<\/h2>\n<p>\t\tPeptiStar is actively developing the use of microwave technology in the manufacturing of Peptide API. In order to drastically shorten chemical reaction time and suppressing required energy, we have jointly developed GMP compliant equipment with Microwave Chemical Co.,Ltd and PeptiDream Inc. This equipment enables the manufacturing of low cost and high quality Peptide API that can meet the needs of clinical trial to commercial scale use.<\/p>\n<div class=\"box-margin-b box-desktop\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave1.jpg\" alt=\"Wave Guide between microwave generating equipment and reaction filtration equipment\" class=\"alignnone size-full wp-image-1034\" width=\"1140\" height=\"797\" srcset=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave1.jpg 1140w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave1-640x447.jpg 640w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave1-320x224.jpg 320w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave1-768x537.jpg 768w\" sizes=\"auto, (max-width: 1140px) 100vw, 1140px\" \/><\/p>\n<p class=\"text-s\" style=\"text-align:center\">Wave Guide between microwave Generator and Filter reactor<\/p>\n<\/p><\/div>\n<div class=\"box-margin-b\">\n<h2 class=\"page-title page-title-bottom-short\">Scaling-up<\/h2>\n<p>\t\t\tWe succeeded in scaling up the Microwave Solid Phase Synthesis equipment that was previously used at the experimental level only. Currently we have 1L, 10L and world leading 30L size equipment in operation. We use Microwave Solid Synthesis Method to manufacture and supply the market with high quality and price competitive Peptide APIs for research grade to commercial scale use.\n\t\t<\/p><\/div>\n<ul class=\"page-peptide-equipment-2col\">\n<li><img loading=\"lazy\" decoding=\"async\" src=\" https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave2.jpg\" alt=\"Automated Microwave Solid Phase Synthesizer\" class=\"alignnone size-full wp-image-1036\" width=\"720\" height=\"901\" srcset=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave2.jpg 720w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave2-511x640.jpg 511w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave2-256x320.jpg 256w\" sizes=\"auto, (max-width: 720px) 100vw, 720px\" \/>\n<p style=\"text-align:center\">Automated Microwave Solid Phase Synthesizer<br \/>CEM Corporation<\/p>\n<\/li>\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave3.jpg\" alt=\"Automated Microwave Solid Phase Synthesizer\" class=\"alignnone size-full wp-image-1037\" width=\"720\" height=\"901\" srcset=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave3.jpg 720w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave3-511x640.jpg 511w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave3-256x320.jpg 256w\" sizes=\"auto, (max-width: 720px) 100vw, 720px\" \/>\n<p style=\"text-align:center\">Automated Microwave Solid Phase Synthesizer<br \/>\uff08PharmaWave-1\/Multi-mode\uff09<br \/>MWCC<\/p>\n<\/li>\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave4.jpg\" alt=\"Automated Microwave Solid Phase Synthesizer\" class=\"alignnone size-full wp-image-1038\" width=\"720\" height=\"901\" srcset=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave4.jpg 720w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave4-511x640.jpg 511w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave4-256x320.jpg 256w\" sizes=\"auto, (max-width: 720px) 100vw, 720px\" \/>\n<p style=\"text-align:center\">Automated Microwave Solid Phase Synthesizer<br \/>\uff08PharmaWave-10\/Multi-mode\uff09<br \/>MWCC<\/p>\n<\/li>\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave5.jpg\" alt=\"Automated Microwave Solid Phase Synthesizer\" class=\"alignnone size-full wp-image-1039\" width=\"720\" height=\"901\" srcset=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave5.jpg 720w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave5-511x640.jpg 511w, https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave5-256x320.jpg 256w\" sizes=\"auto, (max-width: 720px) 100vw, 720px\" \/>\n<p style=\"text-align:center\">Automated Microwave Solid Phase Synthesizer<br \/>\uff08PharmaWave-30\/Multi-mode\uff09<br \/>MWCC<\/p>\n<\/li>\n<\/ul>\n<div class=\"box-laptop box-margin-c\">\n<p><strong>Advantages of MW SPPS Method<\/strong><\/p>\n<ul class=\"ul-blue-check\">\n<li>Improved reaction speed by shortening homogeneous heating time<\/li>\n<li>Shortened manufacturing time by shortening reaction time<\/li>\n<li>Reduction of natural and non-natural amino acid usage<\/li>\n<\/ul><\/div>\n<div class=\"box-margin-b\">\n<ul class=\"ul-technology-link\">\n<li><a href=\"https:\/\/mwcc.jp\/en\/\" rel=\"noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-mwcc.png\" alt=\"Microwave Chemical Co.,Ltd.\" width=\"501\" height=\"429\" class=\"alignnone size-full wp-image-1046\" \/><\/a><span class=\"img-cross\">Joint R&amp;D<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave9.png\" alt=\"\" class=\"alignnone size-full wp-image-1043\" width=\"114\" height=\"114\" \/><\/span><\/li>\n<li><a href=\"https:\/\/www.peptidream.com\/\" rel=\"noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-pd.png\" alt=\"PeptiDream Inc.\" width=\"501\" height=\"429\" class=\"alignnone size-full wp-image-1047\" \/><\/a><span class=\"img-cross\">Joint R&amp;D<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave9.png\" alt=\"\" class=\"alignnone size-full wp-image-1043\" width=\"114\" height=\"114\" \/><\/span><\/li>\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-ps.png\" alt=\"PeptiStar Inc.\" width=\"501\" height=\"429\" class=\"alignnone size-full wp-image-1048\" \/><\/li>\n<\/ul><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Peptide API Manufacturing Technologies MW SPPS Method PeptiStar is actively developing the use of microwave technology in the manufacturing of Peptide API. In order to drastically shorten chemical reaction time and suppressing required energy, we have jointly developed GMP compliant equipment with Microwave Chemical Co.,Ltd and PeptiDream Inc. This equipment enables the manufacturing of low cost and high quality Peptide API that can meet the needs of clinical trial to commercial scale use. Wave Guide between microwave Generator and Filter reactor Scaling-up We succeeded in scaling up the Microwave Solid Phase Synthesis equipment that was previously used at the experimental level only. Currently we have 1L, 10L and world leading 30L size equipment in operation. We use Microwave Solid Synthesis Method to manufacture and supply the market with high quality and price competitive Peptide APIs for research grade to commercial scale use. Automated Microwave Solid Phase SynthesizerCEM Corporation Automated Microwave Solid Phase Synthesizer\uff08PharmaWave-1\/Multi-mode\uff09MWCC Automated Microwave Solid Phase Synthesizer\uff08PharmaWave-10\/Multi-mode\uff09MWCC Automated Microwave Solid Phase Synthesizer\uff08PharmaWave-30\/Multi-mode\uff09MWCC Advantages of MW SPPS Method Improved reaction speed by shortening homogeneous heating time Shortened manufacturing time by shortening reaction time Reduction of natural and non-natural amino acid usage Joint R&amp;D Joint R&amp;D<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":900,"menu_order":48,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"https:\/\/peptistar.com\/?page_id=897","footnotes":""},"class_list":["post-1797","page","type-page","status-publish","hentry","en-US"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/comments?post=1797"}],"version-history":[{"count":10,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1797\/revisions"}],"predecessor-version":[{"id":2184,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1797\/revisions\/2184"}],"up":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/900"}],"wp:attachment":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/media?parent=1797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}