{"id":1836,"date":"2022-10-06T20:06:15","date_gmt":"2022-10-06T11:06:15","guid":{"rendered":"https:\/\/peptistar.com\/?page_id=1836"},"modified":"2022-10-21T00:45:45","modified_gmt":"2022-10-20T15:45:45","slug":"lyophilization","status":"publish","type":"page","link":"https:\/\/peptistar.com\/en\/technology\/lyophilization\/","title":{"rendered":"Mixer-type Lyophilization"},"content":{"rendered":"<div class=\"page-pretitle-lightblue\">\n<p>Peptide and Oligonucleotide API Manufacturing Technologies<\/p>\n<\/p><\/div>\n<h2 class=\"page-title page-title-bottom-short\">Mixer-type Lyophilization<\/h2>\n<p>\t\tLyophilization generally take a long time. Since shelf-type lyophilization equipment has a challenge around homogeneity among trays, a Mixer-type lyophilizer RHEOFREED\u00ae was developed. It was designed to be used for both Peptides and Oligonucleotides and was jointly developed based on the equipment that conducts series of processes. By using this drying method, manufacturing time can be reduced by over 80% when compared to conventional method.  Additionally, it is also effective in resolving the issue of homogeneity.<\/p>\n<div class=\"box-margin-b box-laptop box-gray-border\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-lyophilization1-en4.png\" alt=\"Mixer-type Lyophilization\" class=\"alignnone size-full wp-image-1086\" width=\"1424\" height=\"1211\" \/>\n\t\t<\/div>\n<div class=\"box-margin-c box-laptop\">\n<p><strong>Advantages of Mixer-type Lyophilization<\/strong><\/p>\n<ul class=\"ul-blue-check\">\n<li>Manufacturing time is significantly reduced through reducing time for each of; preparation \u2013 freeze drying \u2013 in-process check \u2013 extraction \u2013 washing processes.<\/li>\n<li>High homogeneity is assured compared to shelf-type lyophilizer (no need for mixing process)<\/li>\n<\/ul><\/div>\n<div class=\"box-margin-b box-laptop\">\n<ul class=\"ul-technology-link-2col\">\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-kobelco.png\" alt=\"KOBELCO ECO-SOLUTIONS Co.,Ltd.\" width=\"501\" height=\"429\" class=\"alignnone size-full wp-image-1087\" \/><span class=\"img-cross\">Joint R&amp;D<img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/08\/technology-microwave9.png\" alt=\"\" class=\"alignnone size-full wp-image-1043\" width=\"114\" height=\"114\"><\/span><\/li>\n<li><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/peptistar.com\/wp-content\/uploads\/2022\/10\/technology-ps.png\" alt=\"PeptiStar Inc.\" width=\"501\" height=\"429\" class=\"alignnone size-full wp-image-1090\" \/><\/li>\n<\/ul>\n<p class=\"text-s text-center-desktop\">*RHEOFREED is registered trademark of KOBELCO ECO-SOLUTIONS Co.,Ltd. Please follow the link below for details.<\/p>\n<p>\t\t\t\t<a href=\"https:\/\/www.kobelco-eco.co.jp\/english\/product\/process\/rheofreed.html\" rel=\"noopener\" target=\"_blank\">https:\/\/www.kobelco-eco.co.jp\/english\/product\/process\/rheofreed.html<\/a>\n\t\t\t<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Peptide and Oligonucleotide API Manufacturing Technologies Mixer-type Lyophilization Lyophilization generally take a long time. Since shelf-type lyophilization equipment has a challenge around homogeneity among trays, a Mixer-type lyophilizer RHEOFREED\u00ae was developed. It was designed to be used for both Peptides and Oligonucleotides and was jointly developed based on the equipment that conducts series of processes. By using this drying method, manufacturing time can be reduced by over 80% when compared to conventional method. Additionally, it is also effective in resolving the issue of homogeneity. Advantages of Mixer-type Lyophilization Manufacturing time is significantly reduced through reducing time for each of; preparation \u2013 freeze drying \u2013 in-process check \u2013 extraction \u2013 washing processes. High homogeneity is assured compared to shelf-type lyophilizer (no need for mixing process) Joint R&amp;D *RHEOFREED is registered trademark of KOBELCO ECO-SOLUTIONS Co.,Ltd. Please follow the link below for details. https:\/\/www.kobelco-eco.co.jp\/english\/product\/process\/rheofreed.html<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":900,"menu_order":49,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"https:\/\/peptistar.com\/?page_id=912","footnotes":""},"class_list":["post-1836","page","type-page","status-publish","hentry","en-US"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1836","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/comments?post=1836"}],"version-history":[{"count":9,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1836\/revisions"}],"predecessor-version":[{"id":2188,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/1836\/revisions\/2188"}],"up":[{"embeddable":true,"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/pages\/900"}],"wp:attachment":[{"href":"https:\/\/peptistar.com\/wp-json\/wp\/v2\/media?parent=1836"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}