Mixer-type Lyophilization

Peptide and Oligonucleotide API Manufacturing Technologies

Lyophilization generally take a long time. Since shelf-type lyophilization equipment has a challenge around homogeneity among trays, a Mixer-type lyophilizer RHEOFREED® was developed. It was designed to be used for both Peptides and Oligonucleotides and was jointly developed based on the equipment that conducts series of processes. By using this drying method, manufacturing time can be reduced by over 80% when compared to conventional method. Additionally, it is also effective in resolving the issue of homogeneity.

Advantages of Mixer-type Lyophilization

Manufacturing time is significantly reduced through reducing time for each of; preparation – freeze drying – in-process check – extraction – washing processes.
High homogeneity is assured compared to shelf-type lyophilizer (no need for mixing process)

Joint R&D

*RHEOFREED is registered trademark of KOBELCO ECO-SOLUTIONS Co.,Ltd. Please follow the link below for details.

https://www.kobelco-eco.co.jp/english/product/process/rheofreed.html